Introduction: Snake bite envenomation is a tropical public health threat that has not been given the real attention. It affects more than 5 million people globally. It presents a public health threat to the Rwandan community, both for humans and animals. Between 2017 and 2018, the Eastern province of Rwanda recorded the highest cases of snakebites among human victims (39%) compared to other provinces. Proper and timely management of SBE can be lifesaving but depends on victims’ health-seeking behavior. Therefore, this research was conducted to assess the health-seeking behaviors of SBE victims bitten in 2022 in the Nyagatare District of Rwanda. Methods: This research was carried out using cross-sectional study design and collected the data between January and December 2022 among 841 participants from Nyagatare District, in the Eastern Province of Rwanda. A quantitative questionnaire was used to assess the healthcare seeking behavior by SBE victims in the study location. A sample size of 462 respondents were determined by Fisher formula. The data was collected, entered, and analyzed by SPSS software version 21. The descriptive and inferential statistic were carried out and the data presentation was done using the tables and figures. The socio-demographic characteristics were analyzed and presented in tables using frequencies and percentages. The Likert scale was used to measure the variables related to health seeking behaviors with 5 points measurement scale. The Likert scale mean level were applied to create the high and the low level of health seeking behaviors. Dependent and independent variables were cross tabulated to measure the level of association with chi-square test of independence. Logistic regression analysis was used to find out factors contributing to healthcare seeking behavior. The significance level was established at the p value less than 0.05 with 95% confidence interval.