Background: Covid -19 pandemic has proved to be great havoc for the people worldwide. The advent of vaccination against Covid -19 has been a ray of hope and the results have been promising in the general population. Pregnant females had not been included in the trial phase initially due to ethical and safety issues. Hence this study was conducted to assess the safety of Covid 19 vaccination in the antenatal period, when its approval was given in pregnant & lactating mothers in India by health authorities. Methods: Pregnant females were divided into 2 groups for study purpose. First group included 100 expectant mothers who got vaccinated against Covid -19 in the antenatal period and the second group included 100 pregnant females who never got vaccinated in spite of encouragement and motivation for the same. Both the groups were compared and analysed for maternal and perinatal outcome. Results: In the current study, we found that the antenatal Covid -19 vaccination did not have any adverse effect on the pregnancy course and did not pose any threat to the foetus in utero, rather it reduced the risk of respiratory distress and neonatal intensive care unit (NICU) admissions of the new-born. As seen in our study, total 36% of the neonates requiring NICU admission for respiratory support, were all born to unvaccinated mothers. Conclusion: Covid 19 vaccination is safe during pregnancy and hence more and more women of reproductive age group should be encouraged for the vaccination.