Statins belong to the class of hypolipidemic drugs, which are the first-line therapy for atherosclerosis, reducing cholesterol and LDL levels in the blood. They are the most studied and safe class of drugs used in the prevention of cardiovascular diseases (CVD), significantly reducing mortality from heart attacks and strokes. It has been found that patients with high lipid levels in the blood have poorer osseointegration of dental implants. Literature data indicate a direct relationship between high lipid levels in the blood and bone resorption due to intermediate products of cholesterol synthesis, slowing bone regeneration. This study examined the influence of statins on implant osseointegration. Articles describing experiments on animals with induced hyperlipidemia using a special diet were analyzed. The results of all the studies we reviewed showed that statins not only reduced hypercholesterolemia levels but also stimulated osteogenesis around the implant by stimulating osteoblasts and inhibiting their apoptosis, as well as inhibiting osteoclasts. Thus, statins can be considered as new, safe, inexpensive, and widely available therapeutic agents to improve implant osseointegration and overall patient quality of life.