This study centers around the detailing and improvement of mouth dissolving tablets (MDTs) for upgrading the dissolvability of antiemetic drugs, especially Piroxicam, utilizing hydrotropic strong scatterings. Hydrotropes like sodium benzoate, ascorbic corrosive, and sodium acetic acid derivation were utilized to work on the dissolvability of Piroxicam, an ineffectively water-solvent medication. Different plans were created utilizing a factorial plan to concentrate on the impact of crospovidone and camphor on basic tablet boundaries like deterioration time and friability. The streamlined bunch (F9) showed fast breaking down (12 seconds) and good mechanical properties, demonstrating its true capacity for worked on understanding consistence and helpful viability. The optimized formulation's robustness was confirmed by stability tests.