Introduction: Acute promyelocytic leukemia (APL) is a subtype of AML characterized by a translocation between chromosomes 15 and 17 [t(15;17)]. In children, APL represents 4% to 8% of pediatric AML cases and about 10% of all APL cases. This case report evaluate the management of a female child with Acute Promyelocytic Leukemia at Ngoerah Hospital, Denpasar. Case Presentation: A 1-year and 9-month-old female was admitted with weakness, paleness, bleeding gums, and lip sores. Examination revealed normochromic normocytic anemia, thrombocytopenia, and fever. Laboratory tests confirmed Acute Myeloblastic Leukemia (AML-M3) and a urinary tract infection, leading to comprehensive therapeutic management. Conclusion: This case report describes Acute Promyelocytic Leukemia in a child with bleeding gums, bruising, severe thrombocytopenia, and Auer rod bundles, diagnosed through medical history, physical examination, and laboratory investigations.