Objective: Aggressive periodontitis comprises a group of rare, severe, rapidly progressive form of periodontitis. Conventional treatment includes mechanical debridement augmented with adjunctive antimicrobial therapy. Development of antibiotic resistance has led to use of lasers. Photodynamic therapy (PDT) is a novel non- invasive therapeutic approach with increased site and pathogen specificity. The aim of this study was to determine the efficacy of photodynamic therapy as adjunctive therapy in aggressive periodontitis after scaling root planning (SRP). Method: Electronic literature searches were conducted 2011 to 2021 using the following database PubMed, Cochrane and Wiley using terms limited to randomized control clinical trials in English and using the PICOS format. The main clinical parameters used were Periodontal Pocket Depth (PPD), and additional clinical parameters using Bleeding on Probe (BOP), Clinical Attachment Level (CAL) were recorded at baseline & third month. Result: The research is conducted to identify all full articles and were done manually from 151 articles, and four studies met the eligibility criteria. The analysis of all studies showed an increase in changes in BOP as the main parameter within three months after baseline. Conclucion: With the available data, it is concluded that photodynamic therapy the statisticallysignificant that PDT may have additional effect on the reduction in pocket depth.