Background: Siddha system of medicine is one of the holistic systems widely being practice in Tamil Nādu and the concept pertaining to drug ingredients are from plant (Mooligai), Metals, Minerals (Thaadhu) and Animal (Jeevam) origin. Traditional medicines require newer standardization, manufacturing, quality control, and scientifically rigorous research to meet standardization. Ettikottai Mathirai(EM) is the polyherbal formulation mentioned in Naam nadu vaithiyam indicated for 18 types of soolai(Pain), Lumbar pain.