Background: This study was conducted to assess the prevalence of class III malocclusion and irreversible pulpitis in a known population and its treatment. Material and methods: This study was conducted to assess the prevalence of class III malocclusion and irreversible pulpitis. This study comprised of 123 participants. The subjects had been explained about the procedure and were asked to give consent. 23 out of 100 subjects refused to provide consent and hence they had been excluded from the study. overall, 100 subjects had been included in the study. All the participants underwent oral clinical examination. The prevalence of class III malocclusion and irreversible pulpitis had been assessed. The findings were tabulated. For the subjects with class III malocclusion, various appliances had been fabricated for treatment, while amongst those with irreversible pulpitis, root canal treatment had been planned. Statistical analysis was conducted using SPSS software. Results: In this study, there were total 100 subjects of which, 56 were male and 44 were female. The prevalence of class III malocclusion was 26%. The prevalence of irreversible pulpitis was 39%. For the treatment of class III malocclusion, Frankel III appliance was given in 13 subjects, chin cup was provided to 8 patients and reverse pull headgear was fabricated for 5 individuals. For the management of irreversible pulpitis, root canal treatment was done in all the subjects. Conclusion: The prevalence of class III malocclusion and irreversible pulpitis in this study was 26% and 39%, respectively. For the treatment of class III malocclusion, appliances like reverse pull headgear, chin cup and Frankel III appliance were given. The subjects with irreversible pulpitis were scheduled for root canal treatment.