The intensive application of pesticides in agricultural practices to meet the food demand of growing world population resulted in accumulation of these pesticides into abiotic environment and biotic entities at different hierarchical levels. These toxic chemical substances are highly carcinogenic and a necessary step should be taken to control the application into agricultural practices. In the present study, the soil samples were collected from 8 different agricultural soils (primarily vegetable crops) of East Godavari, Andhra Pradesh, India during post harvesting time and to evaluate multiresidue pesticides qualitatively using Quick Easy Cheap Effective Rugged Safe (QuEChERS)-Dispersive Solid Phase Extraction (dSPE) clean up combined Gas- Chromatography Mass Spectrometry (GC-MS) method. The physiochemical parameter analysis of all soil samples revealed no observed large-scale variation among all study sites. The GC-MS analysis showed presence of 5 major pesticide compounds namely Terbufos (Organophosphate insectide), Propiconazole (Triazole fungicide), Tebuconazole (Triazole fungicide) Cypermethrin (Pyrethroid insecticide) and Diclofopmethyl (Herbicide). It is evident that the use of restricted pesticides in agricultural operations is still ongoing, and it is essential to regulate this at the fundamental level of agriculture.