An attempt that has continuously expanded over the past ten years has been made to recognize or determine the origin of this disease and to develop pharmacological remedies. Recent advances include enhanced clinical diagnostic criteria and treatment of behavioral and cognitive disorders. Clinically testing a symptomatic treatment that mainly focuses on cholinergic treatment has used randomized, dual, placebo-controlled, parallel-group trials investigating performance-based measures of cognitive performance, tasks of daily life, and behavior. Drugs, such as donepezil, rivastigmine, tacrine, and galantamine, are suggested for patients with Alzheimer's disorder to treat their cognitive deficits. This review emphasized on various recent advancements in terms of treatment , diagnosis and various therapeutic agents which are discussed in use of Alzheimer disease. This review is beneficial for researcher who is doing work on neuroprotective studies.