Volume 8 | Issue - 8
Volume 8 | Issue - 8
Volume 8 | Issue - 8
Volume 8 | Issue - 7
Volume 8 | Issue - 7
Background: Percutaneous mitral valve clipping (PMVC) is being used successfully in the management of severe functional mitral regurgitation (MR) in patients with high surgical risk. However, the impact of (PMVC) on right ventricular volumes and functions is not clear. Aim: The aim of the present study was to assess the impact of (PMVC) (in both short and intermediate terms) on right ventricular (RV) volumes and functions using trans thoracic echocardiography . Methods: The study population included 37 patients with severe (MR), and congestive heart failure who were at high surgical risk. The mean age was 61±14 years. Nine (24.3%) were males. (PMVC) was successfully done for all patients All had clinical and echocardiographic follow up at 6 and 12-months post (PMVC) . Results: MR showed significant improvement after (PMVC) . MR was less than grade II in 29 (78 %) of patients at 6 months and persisted at 12 months (P = 0.0001). Similarly, tricuspid regurgitation (TR) showed marked improvement. Severe (TR) was seen in 29 patients (78%) before), but decreased to 7 patients (18.9%) after (PMVC) (P=0.004). Left ventricular ejection fraction (LVEF) improved from 32.63±13.35% at base line to 36.31±13.28 % at 6 months(P=0.003). This was maintained at 12 months (35.38±91%) Table 1 shows the changes in RV end diastolic volume (RVDV), RV end systolic volume (RVSV) , RV ejection fraction (RVEF), Tricuspid annulus plane systolic excursion(TAPSE), RV longitudinal systolic function by tissue Doppler imaging(TDI) as well as peak systolic pulmonary artery pressure (PASP). Conclusion: (PMVC) induced a significant reverse remodeling of RV by decreasing both ( RVDV) and (RVSV) Moreover, it improved longitudinal RV systolic function as well as (RVEF). This was maintained up to one year follow up.