Autoimmune diseases, where the immune system mistakenly attacks the body's own cells, are complex and often require a multifaceted treatment approach. While conventional medicine primarily focuses on managing symptoms and suppressing the immune response, complementary therapies like Energy healing and siddha medicine has emerged as a promising approach to the holistic treatment of autoimmune diseases. The amalgamation of these modalities aims to address the root cause and restore body balance. In this review article, we explore the principles and practices of Siddha Vaidyam, an ancient Indian healing tradition, in addressing autoimmune conditions. We delve into the concept of energy blockages, its flow, the role of energy points and therapeutic touch, lifestyle modifications, and dietary regimens advocated by Siddha Vaidyam. Through a comprehensive analysis of research studies, case reports, and anecdotal evidence, we highlight the potential benefits and challenges of applying Siddha principles in the management of autoimmune diseases. This review aims to provide insights into the effectiveness of the amalgamation of energy medicine and therapeutic sessions in enhancing the well-being and quality of life of individuals with autoimmune conditions.