Sanitary napkins are indispensable for menstrual hygiene, providing comfort and protection during menstruation. However, concerns have been raised about their potential side effects on women's health. This review paper explores sanitary napkins' various physical, chemical, and psychological impacts. Physical side effects include allergic reactions, skin irritation, infections, and rashes, often caused by synthetic fibers, adhesives, and prolonged use. Chemical exposure to dioxins, furans, volatile organic compounds (VOCs), and pesticide residues from the cotton used in manufacturing raises significant health concerns, including cancer risk, endocrine disruption, and respiratory issues. Psychologically, the fear of leakage and odor can lead to anxiety and stress, while societal stigma around menstruation may affect body image and self-esteem. Environmental implications are also noteworthy, as most sanitary napkins are non-biodegradable, contributing substantially to plastic waste. Mitigation strategies include the use of organic and natural products, frequent changing of napkins, improved product design for better breathability and hypoallergenic properties, and increased education and awareness about menstrual hygiene practices. This review emphasizes the need for ongoing research to understand the long-term health effects of sanitary napkins and calls for the development of safer, more sustainable menstrual products. By addressing these issues, we can enhance women's health and well-being while also considering environmental sustainability.