Objectives: The study was performed to evaluate the efficacy of the tamsulosin vs silodosin in the Benign Prostate Hyperplasia and the patients suffering from the ureteric stones. Methodology:An observational study was performed on 210 patients for a period of 6 months visiting the Department of Urology , Adesh Institute of Medical Sciences and Research , Adesh Hospital , Bathinda. Results: Out of Silodosin and Tamsulosin. Silodosin[75(73.5%)] is mostly prescribed in Benign Prostatic Hyperplasia patient followed by Tamsulosin [27(26.5%)].Out of Silodosin and TamsulosinSilodosin [55 (51.9%)] is mostly prescribed in ureteric stoneparticipants followed by Tamsulosin [515 (48.1%)].Conclusion: Silodosin are much safer and effective as compared to Tamsulosin. After therapy is completed patients recovered from the symptoms of Benign Prostate Hyperplasia and Ureteric Stones. Both treatments went over well.