Shwaskuthar Rasa [SKR] is a herbo-mineral ayurvedic formulation indicated in the treatment of Shwas, Tamakshwas[~BronchialAsthma],Kasa[cough]andalliedrespiratoryconditions.Specificmineral and herbal drugs along with Marich [Piper nigrum] are processed to formulate themedicine. However, variations in quantities of ingredients and preparation methods have been revealed in ayurvedic classical literature. In onepreparation method of SKR it is suggested toaddone one kernels of Marich in given quantity to the whole mixture of formulation. However, generally in pharmaceutical practice Marich fine powder is mixed directly. Thus, in present study the attempt is made to establish standard preparation method of SKR and to generate qualitystandards. Three samples of SKR were prepared with different quantities and forms of Marich.These samples and market sample of SKR were analyzed in laboratory using physico-chemical, phytochemical tests and HPTLC technique. Physicochemical and phytochemical analytical values of all four samples were nearby alike. However, S3 sample prepared with aqueous extract ofMarich showed less percentage of Piperine and S1 sample showed comparative less percentageof Shogaols than three other samples. Slightly higher value of Piperine was noticed in S1 samplethan S2 and S4. Considering the property of Piperine as bio enhancer, S1 sample may be helpful to increase bioavailability and efficacy of the formulation. Thus, it is interpreted that the method stated in traditional formula could be useful toproducedesired effect.