Pyrazolines are a significant class of heterocyclic compounds with vital biological activities. The literature has proven that compounds with an s-triazine core containing other heterocyclic compounds frequently exhibit significant biological activities. s-triazine and pyrazoline both are major structural core systems found in many pharmacologically active Compounds. In the present study, Pyrazoline derivatives are coupled with 4-hydroxy Coumarin comprising s-triazine molecule which contributes to enhance pharmacological activities of Pyrazoline. On the basis of literature survey new molecules were designed and successfully synthesized in the laboratory using convenient synthetic protocols and structures were confirmed by 1HNMR, IR and Mass Spectroscopy. All Synthesised compounds (9a-j) were screened for Anti-Bacterial and Anti-fungal activities.