ISSN : 2663-2187

SYNTHESIS AND CHARACTERIZATION OF A NOVEL NANOCOMPOSITE USING SILVER NANOPARTICLES, SODIUM ALGINATE AND PAPAYA LEAF EXTRACT AND ITS ANTIOXIDANT POTENTIAL

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Dr. Pooja Singh, Dr. Kiran Kumar Pandurangan, Dr. Dhanraj M. Ganapathy
» doi: 10.33472/AFJBS.6.11.2024.1612-1620

Abstract

Introduction: The biomedical field has witnessed a surge in research focusing on tailored nanomaterials, owing to the remarkable versatility of nanotechnology. These materials find applications across a spectrum, from disease treatment to enhancing product performance. Among them, silver nanoparticles (AgNPs) have gained prominence as effective antioxidant and antibacterial agents, thanks to their unique physicochemical properties. The goal of this research is to examine the antioxidant potential of silver nanocomposite containing sodium alginate and Carica papaya leaf extract. Materials and Methods: The research involved using silver nitrate, Mueller Hinton Agar, and Carica papaya leaves obtained from Tamil Nadu, India. Extracts from Carica papaya leaves were prepared, and silver nanoparticles (AgNPs) were synthesised using eco-friendly methods. Sodium alginate was added to create a silver sodium alginate nanocomposite. The characterization process included UV-Vis spectroscopy, and antioxidant properties were checked using the DPPH assay (1,1-diphenyl-2-picrylhydrazyl). Results: Carica papaya-mediated silver nanoparticles (AgNPs) and sodium alginate nanocomposite were successfully synthesised. Visual examination confirmed colour changes, validating AgNP formation. UV-Vis spectroscopy revealed a peak at 420 nm, indicating AgNP presence and nanocomposite formation. The DPPH assay demonstrated antioxidant activity of AgNPs, comparable to ascorbic acid, with no significant differences observed in absorbance between AgNPs and controls (p > 0.005). Conclusion: This research underscores the promising potential of Carica papaya-mediated silver nanocomposites, showcasing their comparable antioxidant activity to the control. The environmentally friendly synthesis approach holds significance for biomedical applications, paving the way for innovative developments in nanotechnology.

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