ISSN : 2663-2187

Synthesis, Spectral Characterization and Anticancer activities of Isoniazid-based Schiff Base

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M. SUGANYA, G. PUTHILIBAI
ยป doi: 10.48047/AFJBS.6.8.2024.2505-2514

Abstract

A new Schiff base ligand based on isoniazid was synthesized by the condensation of 5X - thiophene-2-carboxamide (1 mmol) (where X= acetyl-N-(adamantan-2-yl)) and isoniazid (1 mmol). The synthesized ligand and metal complexes were characterized by 1H NMR, mass spectral, FT IR spectral studies. The synthesized Schiff base ligand was evaluated for its anticancer activities, showed the moderate levels of cytotoxicity activity.

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