The goal of the current investigation was to determine whether methomyl, when given orally to female albino rats during organogenesis (from the sixth to the fifteenth day of gestation), was hazardous to development and whether Curcuma longa might have a protective effect against methomyl teratogenicity effects. The morphological analysis of the uterus and fetuses was evaluated. The number of implantation sites, resorption sites, pre-and post-implantation loss, and late resorption sites was observed. The fetuses were additionally checked for skeletal issues. The number of corpora lutea per dam treated with Curcuma longa increased significantly. Late resorption sites were significantly elevated in the single oral dose of methomyl equivalent to 1/20 LD50 when compared to the Curcuma longa groups. Compared to the Curcuma longa groups, a substantial increase in the percentage of post-implantation loss per dam and external abnormalities in fetuses derived from dams given methomyl were observed. The dose of methomyl (1/20 LD50) groups was observed in the xiphosternum, wavy ribs, and partial or absent sternal ossification. From these findings, Curcuma longa plays a critical role in mitigating the effects of methomyl during the organogenesis phase.