ISSN : 2663-2187

The Concanavalin A-Induced Autoimmune Hepatitis Model in Mice: Historical Perspectives, Experimental Insights and Molecular Mechanisms

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Mohamed Galal Mansi, Dina Saad El-Agamy, Wael Mohamed Elsaed, Rania Naeem Sherif
» doi: 10.48047/AFJBS.7.7.2025.510-518

Abstract

The Concanavalin A (Con-A)-induced autoimmune hepatitis (AIH) model is a well-established experimental tool for studying immune-mediated liver injury. This review provides a comprehensive overview of Con-A, including its biochemical properties, historical discovery, and evolution into a valuable research model.

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