Background: Parkinson’s disease is a progressive neurological disorder which affects many systems of the Human Body including Voice and Swallowing systems. Many patients are not even aware of the deterioration occurring in their body due to the progressing Parkinson’s disease. Objective: To find out the effect of Progression of Parkinson’s disease on Swallowing and Voice Methods: A Cross-Sectional study was conducted using Non-Probability convenience sampling technique in 4 Hospitals of Multan. A sample of 172 Parkinson’s patients were enrolled into the study by their informed consent. After filling the Demographic sheet, Patients were given three Questionnaires of Mini Mental Scale Examination (MMSE), Voice Handicap Index and Dysphagia Handicap Index in order to rate the handicapping effects of Parkinson’s disease duration on their Voice and Swallowing. Data Analysis was done by using SPSS 21.0 statistical software. Results: The results of the study showed significant impact of Parkinson’s disease duration on Voice. The physical and Functional parameters of Voice Handicap Index are significantly affected. The results showed that emotional parameter of Dysphagia handicap index is significantly affected by disease duration. It also showed the positive correlation of VHI and DHI measurements in PD duration groups. Conclusion: The results of the study concludes that increasing duration of Parkinson’s Disease affect the Voice significantly than Swallowing. It will help in determining the Voice and Swallowing related bodily changes like Silent Aspiration, Vocal fold paralysis etc. of patients with increasing duration of Parkinson’s disease. Hence it will help in making better treatment plan for these patients.