the article aims to identify the effect of using a therapeutic and rehabilitative exercise program accompanied by modern manual therapy for lower back pain resulting from lumbar disc herniation and to reach: Reduction and disappearance of sciatica pain associated with back pain resulting from disc herniation. Restoring the flexibility of the lumbar region and improving its range of motion. Speeding up recovery and not resorting to surgical operations. The sample was chosen intentionally from the visitors to the private medical center for the treatment of musculoskeletal diseases in North Sinai Governorate, Arish City, who were suffering from sciatica pain in the age group (20-30) years, men and women, where the injury was recent and they had not suffered from it before and was not chronic, and its number was 16 patients. The results indicated that significance of the differences between the pre- and post-measurements in some variables. There are statistically significant differences in favor of the post-measurement over the pre measurement in the selected measurements under study. Conclusion. The proposed program (therapeutic and rehabilitative exercises and modern manual therapy) has a positive effect on treating sciatica pain resulting from lumbar disc herniation.