ISSN : 2663-2187

TO STUDY THE LEVEL OF SERUM URIC ACID IN HEALTHY AND DIABETIC PATIENTS, URIC ACID: A PREDIABETIC MARKER

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Bajpai Sourabh,Gautam Kumar Das, Harsha M Ghanti, JafriTanveer Raza,Satyawan, Andriyas Ekta
» doi: 10.48047/AFJBS.6.Si4.2024.4483-4493

Abstract

Introduction: In India about 39% of the population is suffering from obesity among which approx. 11% are diabetic and nearby 15% are pre-diabetic. These metabolic disorders are somehow related to the production of reactive oxygen species in individuals.The production of excessive amounts of Reactive oxygen species is responsible for development of many diseases including Diabetes, Neurodegenerative Disorders, Cancer etc. Uric acid is also a Reactive oxygen species although along with it also shows antioxidants property, the formation of uric acid normally takes place as end product of purine metabolism. We hypothecally sate that there is correlation in diabetes and uric acid metabolism. Aim and Objective: This study was conducted to identify the correlation of Serum Uric Acid (SUA), in diabetic and healthy individuals. Material andMethods: A total of 150 blood samples were collected and all the samples were analysed for FBG by the GOD-POD Method and HbA1c Method. The samples were analysed for Serum Uric Acid (SUA) by Uricase enzymatic Method concentrations that were used for correlative study. Results: In the present study it was observed there was a significant difference in the value of serum uric acid in all different groups. Conclusion: The Study showed correlation of HbA1c, SUA in Diabetic, Pre- Diabetic &NonDiabetic conditions.

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