Background: Cardiac chest pain may be caused by either coronary artery disease (CAD) or non-CAD related etiologies. Aim: To identify the role of CTA coronary arteries in management plan of high and moderate risk coronary artery disease patients and prediction of coronary artery pathology in angina patients presenting with chest pain. Patients and methods: This was a cross-sectional analytic study conducted on 50 patients presented with signs and symptoms suggestive of stable angina at Radiology department at Suez Canal University Hospitals and Zagazig University Hospitals. Results: The overall SIS of the study population was 2.14± 2.71. Most of the patient had less than 2 segments involved (66%). 20% of the patients had high risk plaque while 50% of the patients had stable plaque. Regarding the morphology of the plaque, 20% of the population had two or more features for diagnosis. There was significant positive correlation between CAD-RADS and high risk plaque, the stability of the plaque, the degree of stenosis, CVD risk and Framingham risk score p<0.001. Conclusion: CT coronary angiography could be considered as a good non invasive predictor for further plan management for coronary disease patients.