Vaginal agenesis seen in Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a condition with significant psychological and social consequences where there is embryonic underdevelopment of müllerian duct. Mayer- Kuster- Hauser (MRKH) syndrome is an uncommon congenital condition characterized by agenesis of mullerian structures, uterus and upper 2/3rd of vagina with fully developed secondary sexual characteristics and is one of a cause for primary amennorhea. Normalizing sexual life with vaginal reconstruction to adequate length is usually the treatment of choice. Among many non-surgical and surgical options available, McIndoe vaginoplasty is the commonest surgical management performed with the use of amnion as a graft. Here we present a case series of 3 women with MRKH syndrome with vaginal agenesis treated with a successful amnion graft vaginoplasty.