One dangerous side effect of diabetes is diabetic foot ulcers. Patients with diabetic foot ulcers frequently develop multidrug-resistant organisms (MDROs) as a result of the ulcer's long healing process, improper antibiotic use, repeated hospital stays, neuropathy, nephropathy, and peripheral vascular disease. Objective: The aim of this research is to examine the potential antibacterial qualities of oil medicinal plants extracts and their prospective as a source of additional anti-infection compounds. Results: forty-nine isolates from each bacterial group (Escherichia coli, pseudomonus spp., Proteus mirablis, Staphylococcus aureus) isolated from diabetic foot ulcer and recorded resistance to different antibiotic categories. These isolates treated with four kind of essential oil plant extracts which were (Syzygium Aromaticum (Clove), Camellia sinensis (green tea), Nigella sativa (Black caraway) and Allium sativum (garlic)). the result of Scanning electron microscopic (SEM) images showed a normal shape of cells not treated with any type of ethanolic plant extracts where it appeared without any change in morphological appearance While the results of the microscopic examination showed that the presence of media containing microorganism treated with ethanolic plant extracts caused cell deformations, wrinkles, loss of cell shapes and malformations (increases in length and decrease in width) preposition E. coli while SEM showed cell depressions, loss of regular cell shapes. Erosion on the outer surface of cells indicates the death of cells and loss of cellular contents in case of Pseudomonas aeruginosa As for staph. aureus SEM showed cell depressions and dimples on outer surface of the cells. on the other hand, irregularities, diminished cells number and perforation on the outer surface of cells were detected also showed formation of depressions and dimples on the outer surface of the cells. However, abnormalities, a decrease in the number of cells, and perforation on the outer surface of the cells were observed in proteus mirabilis