M. oleifera & Moringa Pteridosperma tree has a wide range of therapeutic applications, including both prevention and therapy. Its bark, seeds, oil, sap, leaves, roots, and flowers, gums are used in conventional medicine. It provides an immediate remedy for stomach ulcer, gastric ulcer and other type of ulcer. it provides the therapeutic treatment of the ulcer disease. Objective: The study's goal was to assess the function of M. oleifera & Moringa Pteridosperma in the treatment of anti ulcer activity. The article summarised numerous pre-clinical report, clinical trials reports, in addition to the mechanism of action to provide an overview of Moringa Oleifera & Moringa Pteridosperma usefulness in the treatment of anti- ulcer activity. Methods: The information for their review articles was acquired by using Google Scholar and PubMed as search engines, as well as a number of publishers, including Springer Nature, Bentham Science Taylor & Francis, and Elsevier. Clinical trails.gov.in was referred to study the clinical trials data and pre-clinical trail data as a search engine. Results: M. oleifera & Moringa Pteridosperm plants is useful for anti-ulcer activity prevention and treatment due to its anti-inflammatory, antibacterial, and antioxidant features for plant. M. oleifera & Moringa Pteridosperma plants can be used as an alternative to treat ulcer and its related physiological effects such as antibacterial effect, inhibiting the growth of helicobacter pylori healing effect and various pre-clinical and clinical studies have been summarized that have demonstrated that using M. oleifera & Moringa Pteridosperma significantly improved the mentioned parameter. Conclusion: M. oleifera & Moringa Pteridosperma is an herb that may be used to treat antiulcer activity and its associated negative effects. More preclinical and clinical research, however, might contribute to raising awareness and management of Moringa.