Liquisolid technique has shown promise for improving the solubility and bioavailability of medications that are water insoluble. The thorough analysis examines the most current developments in liquisolid technology, emphasizing its guiding principles, approach to formulation, and techniques for characterization. The liquisolid method solves major formulation issues by transforming liquid drugs into dry, free-flowing, and compressible powder types. We look over the benefits, including higher rates of drug release and increased bioavailability, as well as the drawbacks, like formulation complexity and stability issues. Advances in technology and novel materials for coating and carriers have led to a greater range of uses for liquisolid systems in the pharmaceutical sector. The study also includes a number of pharmacokinetic studies that show how well liquisolid formulations work in comparison to traditional techniques. There is still lots of scope for growth and research in this area, despite current obstacles. With a focus on the necessity for ongoing research and development to fully realize the potential of liquisolid techniques in drug delivery systems, this study seeks to present a thorough grasp of the state of the art in this field.