Femur is the strongest bone in the body. Morphometric evaluation of proximal femur have predictive role in determining fracture risk. Morphometric parameters of proximal femur are affected by several factors such as age, BMI, calcium, vitamin D and bone mineral density. Thus, the aim of this study was to evaluate femoral morphometry and its relationship with BMD and serum levels of calcium and vitamin D. Materials and methods: This study was conducted in the Department of Anatomy and Department of Orthopedics, Rama Medical College and Research Center,Rama University, Mandhana, Kanpur, UP. Total of 200 healthy women between the age of 25-64 years were included. Details of participants like age, BMI, menstrual status were noted and femoral morphometric parameter like hip axis length (HAL), femoral neck axis length (FAL), femoral neck width and length (FNW, FNL) and femoral neck shaft angle (FNSA) were evaluated. Serum calcium and vitamin D were measured using standard kit-based method and bone mineral density was measured by DEXA. Result: In this study, the level of serum calcium, vitamin D and BMD were significantly high in premenopausal women. 14.4% and 23.3% of premenopausal women and 47.3% and 60.9% of post-menopausal women were vitamin D and calcium deficient respectively. 46.6% and 33.3% of premenopausal women were osteoporotic and osteopenia respectively while the same were 55.4% and 36.4% in postmenopausal women. Proximal femoral morphometry correlated significantly and positively with BMD. The correlations of BMD with calcium and vitamin D were also significantly positive in the study participants. Conclusion: Deficiency of vitamin D and calcium is associated with altered bone structure and mass. Hence, adequate intake of both calcium and vitamin D is needed maintain the normal bone morphometry