ISSN : 2663-2187

A STUDY ON SERUM ZINC AND MAGNESIUM STATUS WITH GLYCATED HEMOGLOBIN OF TYPE-2 DIABETES MELLITUS PATIENTS AMONG ROHILKHAND POPULATION

Main Article Content

Saurav Rai, Biswajit Das, Sumit Yadav, Mohd Ajmal, Ashish Kumar Sharma
ยป doi: 10.48047/AFJBS.6.12.2024.1595-1600

Abstract

Aim: This study looks at the relationship between glycemic markers and serum zinc and magnesium levels in patients with Type-2 Diabetes Mellitus (T2DM) in the Rohilkhand region. Methods: Serum separated from plain vial after centrifugation was used for estimation of serum zinc by colorimetric method, serum magnesium by Calmagite method; Plasma glucose estimation by GOD-POD Method, End Point, Glycated hemoglobin by Particle enhanced immune turbidimetric method on Automated Analyser ERBA EM360. Results and conclusion: Serum magnesium and zinc levels were found to be significantly lower in T2DM patients than in non-diabetic controls. Serum magnesium and zinc levels showed a positive correlation, pointing to a possible interaction or co-regulation of these micronutrients. Serum zinc levels and glycemic markers, such as HbA1c, fasting plasma glucose, and postprandial glucose, did not, however, show any discernible association. These results suggest that, while not directly affecting glycemic control, deficiencies in magnesium and zinc may play a part in the metabolic changes linked to type 2 diabetes. To fully comprehend the underlying mechanisms and possible clinical implications of these micronutrient deficiencies in the management of diabetes, more research is required.

Article Details