Various technologies and materials have been developed with the goal of repairing and reconstructing tissue loss in patients with periodontitis. Periodontal guided bone regeneration (GBR) and guided tissue regeneration (GTR) involve the utilization of a membrane to prevent epithelial cell migration, thereby maintaining space and creating a protected environment conducive to tissue regeneration. Over time, the manufacturing procedures of these barrier membranes have undergone significant improvements.Three-dimensional (3D) printing technology has resulted in significant advancements in periodontal regeneration techniques. The process of three-dimensional (3D) printing involves constructing 3D objects through additive manufacturing techniques. While its application spans various dental specialties such as endodontics, maxillofacial surgery, prosthodontics, orthodontics, and restorative dentistry, our review article focuses specifically on its use in periodontology. A comprehensive literature search was conducted on PubMed/Medline and Google Scholar using diverse key terms. The majority of selected studies were either in vitro, preclinical, case reports, retrospective, or prospective studies, with a limited number of clinical trials also being conducted. Periodontal applications of 3D printing encompassed educational models, scaffolds, socket preservation, sinus and bone augmentation, and guided implant placement. The findings revealed several advantages, including improved alveolar ridge preservation, enhanced regenerative capabilities, significant reduction in pocket depth and bony fill, simplified implant placement in complex cases with greater precision and efficiency, reduced procedure time, and improved outcomes.