Numerous medicinal plants have shown promise in treating a wide range of illnesses due to the presence of active components. Phenols, coumarins, lignans, essential oil, monoterpenes, glycosides, flavonoids, organic acids, lipids, alkaloids, and xanthenes are among the chemical components found in liver-protective plants. Since many plants and formulations are purported to have hepatoprotective properties, there has been a significant focus on developing hepatoprotective medications derived from plants on a global scale. Traditional medicine makes extensive use of Aloe barbadensis for a variety of conditions, one of which is its hepatoprotective action. Capsules of Aloe barbadensis were prepared and tested for organoleptic qualities and other metrics. Results from the finest in-vitro dissolution tests showed that the Aloe barbadensis extract medicinal herbs capsules could be a promising new phytotherapy strategy for hepatoprotective effects, with a rate of 89% after 10 minutes in acid medium. The current study demonstrates that the aqueous extract of Aloe barbadensis has a substantial ability to restore the integrity of hepatocytes, as demonstrated by improvements in physiological parameters, excretory capacity (BSP retention) of hepatocytes, and stimulation of bile flow secretion.