The dynamics of the consumer market evolved with globalization. But among its long-term impacts are changes in diet and lifestyle. Research in the chemical and pharmaceutical sciences has led to the development and discovery of medicines that have saved millions of lives. However, extended use of these drugs has raised questions about their safety and potential toxicological consequences. To validate their traditional usage, researchers examined the herbs that were previously used in Chinese and Ayurvedic medicine. As a result, communities' reliance on complementary and alternative medicines has started to resurrect during the previous several decades. Most often, synthetic medications like aspirin and paracetamol are used to treat fever. Numerous adverse consequences are linked to synthetic medications. Because they are easily accessible and have fewer side effects, herbal medications provide an alternate method of therapy. The purpose of this study was to ascertain the hydroalcoholic leaf extract of Scutia myrtina's antipyretic efficacy in albino rats. Because the plant extracts include potentially bioactive components, the current investigation shows that they have notable antipyretic action. Our studies also revealed that Scutia myrtina leaf hydroalcoholic extract had notable antipyretic effects that were dosage dependant.