In present times Liver diseases are increasingly more predominant, round about 2 million people are demising from liver diseases widely every year. Inclusively 1 million people due to complication of cirrhosis and 1 million due to viral hepatitis, etc. An observational prospective study was conducted to find out the risk actor bring about liver disease. A hospital based coordinated prospective study cases were focused among CLD cases from October 2022 to march 2023. A total 240 subjects are taken in this study from general medicine department in tertiary care hospital. Data on patient’s demographics, occupation, past medical history and consumption of Ayurveda medicine was collected using a structured questionnaire after getting informed written consent. Results: A total of 240 patients were screened to include the subjects in the study. The results of the present study include demographic distribution of patients, the role of a clinical pharmacist in lifestyle modification and disease outcome. Statistical analysis was done and proved the influence of clinical pharmacist role on disease outcome reduce the risk of hepatic diseases in people. It was found that among all subjects (240) most of the subjects are seen in 41-50 years group with 88 subjects (36.66%) are higher among all age groups were observed. Followed by 51-60 years age group with 57 subjects (23.75%) were observed. Conclusion: From this study we can conclude that the highest effect on liver was found by the consumption of ayurvedic medicine for greater than 2 months from their past medical history, out of 240 subjects 90 subject (37.5%) were on Ayurvedic medicine. The most effected subjects are of alcoholic liver disease. Also patient’s with occupational factors exposed to stress diagnosed with liver diseases are mostly seen in daily wage workers with 77 subjects (32.80%).