Northeast India is renowned for its rich cultural diversity and vibrant ethnic populations. The region is home to numerous indigenous communities, each with its own distinct social structures, languages, customs, and traditions. Cardiovascular disease continues to hold its position as the foremost cause of death among both men and women in both developed and developing nations, a troubling trend that warrants serious concern. Northeast India is not exempt from this trend. It is crucial to unveil the various factors associated with cardiovascular diseases due to their significant impact. The current study focused on women from the Deori and Kalita populations living in Assam, Northeast India, aiming to illustrate cardiovascular risk factors through diverse anthropometric indices. Anthropometric and physiological data were collected from total of 871 premenopausal married women aged between 18 to 49 years as part of the study. The anthropometric indices were utilized to assess both general and abdominal obesity, which are known to be associated with cardiovascular diseases. General obesity, as determined by BMI, has been identified as a significant risk factor for cardiovascular health in both population groups. Among the Kalita population, WHR and WHtR were identified as effective cardiovascular risk screening tools, as evidenced by the elevated odds ratio for pre-hypertension. The study suggests that anthropometric indices could serve as useful markers for overall health status and effective screening tools for assessing cardiovascular risk among women.