The region under study is marked by agricultural activity, where farming is the primary occupation of its inhabitants. This study aims to determine the suitability of surface waters in the watershed of DjedraWadi and its tributaries for irrigation. Hydrochemical analysis was conducted at seven stations over four sampling campaigns extending from November 2020 to December 2021. These analyses included pH, electrical conductivity, TDS, major element concentrations, nutrients, and five trace metal elements (Mn, Zn, Pb, Cr, and Cd). The suitability of these waters for irrigation was also assessed based on water quality indices such as sodium adsorption ratio (SAR), residual sodium carbonate (RSC), permeability index (PI), sodium percentage (Na %), Kelley ratio (KR), magnesium hazard (MH), and potential salinity (PS). High levels of electrical conductivity, HCO3-, NO3-, and Cl- recorded may influence the yield and quality of certain vegetable crops and fruit trees. Statistical analysis enabled us to identify the group of stations whose waters may contribute to decreased permeability, which could lead to long-term deterioration of soil structure.