Hypertension is a major risk factor for cardiovascular diseases, necessitating effective management strategies to mitigate associated morbidity and mortality. Lifestyle modifications are advocated as first-line therapy for hypertension control, yet their real-world effectiveness remains underexplored. Objective: This population-based study aimed to evaluate the effectiveness of lifestyle modification interventions in achieving blood pressure control among individuals with hypertension. Methods: A prospective cohort design was employed to assess the impact of lifestyle modification interventions on blood pressure control. Participants were recruited from the tertiary care facility. Baseline data on demographic characteristics, medical history, lifestyle habits, and anthropometric measures were collected. Lifestyle modification interventions, including dietary modifications, physical activity promotion, smoking cessation support, and stress management techniques, were implemented. Follow-up assessments were conducted at regular intervals to monitor changes in blood pressure levels, anthropometric measures, and lifestyle habits. Results: Significant reductions in both systolic and diastolic blood pressure levels were observed following lifestyle modification interventions. Anthropometric measures, including weight, waist circumference, and BMI, showed significant improvements post-intervention. Additionally, participants exhibited favorable changes in lifestyle habits, such as increased adherence to the DASH diet, engagement in regular exercise, smoking cessation, and stress management practices. Conclusion: Lifestyle modification interventions play a crucial role in achieving blood pressure control and improving cardiovascular health outcomes among individuals with hypertension. These findings underscore the importance of integrating lifestyle modifications into hypertension management strategies for effective prevention and control of cardiovascular diseases.