Background: To study the assessment and co-relation of thyroid function parameters in patients with first trimester vaginal bleeding and to study its pregnancy outcome. Method: The prospective observational study was conducted in the department of obstetrics and gynecology, MRAMC Ambedkar nagar during one year period from march 2023 to march 2024 with the sample size of 151 patients who fit the inclusion criteria were included in the study after obtaining an informed and written consent. Results: Among the 151 patients, a total of 89 (58.94%)were Euthyroidism, 57 (37.75%) were hypothyroidism, 3 (1.99%) were hyperthyroidism and 2 (1.32%) were patients with autoimmune thyroid disease. Among the 151 patients, 18 (31.58%) with hypothyroidism and 2 (100%) with autoimmune thyroid disease tested positive for TPO antibodies. . Abortions occurred more frequently in hypothyroidism in 24 patients (42.11%) followed by 9 in euthyroidism (10.11%). In normal TSH levels i.e Less than 2.5 μIU/L, abortion was found in 27.27%. Moreover the TSH more than 2.5 μIU/L was found significantly more in aborted as compared to continued pregnancy.The Anti-TPO antibodies level more than 9 IU/ml was significantly more (48.48%) in aborted as compared to continued pregnancy (3.39%). Conclusion: There is positive correlation between thyroid disorders and adverse outcome in early pregnancy. The patients are in increased risk of having miscarriage in early pregnancy. Among the thyroid function test parameters ,serum TSH and anti TPO Antibodies have positive correlation with adverse outcome like miscarriage in early pregnancy .Hence Serum TSH And Anti TPO antibodies can be used as predictor for adverse outcome in early pregnancy so it can be routinely recommended for screening for adverse outcome in the first trimester.