Background: Urinary tract infections (UTIs) are the major health problems in young people. Aim: To assess the Assessment of Knowledge regarding urinary Tract Infection among School Students of Jerash Governorate. Methods: A cross sectionaldescriptiveresearch was carried out among 208 students of all school students at Jerash governorate school. Tool: contain two parts;socio-demographic characteristics sheet and questionnaire that takes care of the data to assess their knowledge, and it consists of (22) items. Each item has three options: Agree, Neutral, or Disagree. Results:The majority of the studied students were from 13 to 18 years old, female, and living in rural areas. Regarding parent's education highest percentage of studied school children was Bch degree and regarding family income the majority of studied school children majority were 500 - 1000 JD. Conclusions: The studied students had low level of knowledge regarding UTI with no relation with their sociodemographic data except their parents’ educational and income levels. Recommendations: Based on the results, prepare educational programs for the school students of Jerash governorate to develop their knowledge of the seriousness of urinary tract diseases, as well as establish units dedicated to counseling and healthy habits.