ISSN : 2663-2187

ASSOCIATION OF CARIOVASCULAR RISK FACTORS AMONG REPRODUCTIVE AGE GROUP WOMEN WITH PCOS IN KASHMIR VALLEY ,AN ANALYTICAL AND PRESPECTIVE CASE CONTROL STUDY.

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MUNEERA RASOOL, DR. NAVNEET SHARMA, DR. SHAJRUL, DR.TAHIR AHMAD GANAYIE
» doi: 10.48047/AFJBS.6.10.2024.7108-7113

Abstract

Polycystic Ovarian Syndrome (PCOS) is associated with reproductive and metabolic abnormalities.PCOS is one of the most common endocrine diseass in women ,affectingupto 10% of women in reproductive age .PCOS is characterized by chronic anovulatory cycles ,oligo – or amenorrhea, hirsutism,an insulin resistance ; obesity is also common .PCOS not only has a negative effect on fertility,but it is also considered aclear cutplurimetabolic syndrome ,being associated with type 2 diabetes mellitus ,hypertension and dyslipidemia. Insulin resistance is probably the major risk factor for the occurance of cardiovascular disease (CVD) in PCOS.The risk of coronary artery disease and myocardial infarction has been reported to be increased in patients with PCOS compared with regularly cycling women even if mortality because of circulatory disease does not seem to be increased .In PCOS women , endothelial and diastolic dysfunction have been shown and associated with both elevated androgen levels and insulin resistance . Recently ,together with classic Cardio vascular (CV) risk factors ,such as Total Cholesterol (TC) and High Density Lipoproteincholesterol ( HDL –C) levels ,obesity ,homocysteine ,and left ventricular hypertrophy LVH have been shown to be independently associated with CV risk . LVH is an important predictor of CV morbidity and mortality.

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