Hypertension (HTN) is defined as the systolic blood pressure (SBP) values of 130 mm Hg or more and/or diastolic blood pressure (DBP) of more than 80 mm Hg. Various research studies have shown the conflicting result about association of serum uric acid with blood pressure in essential hypertensive subjects. Hence, this study was conducted to find the association of serum uric acid with blood pressure in essential hypertension. MATERIAL AND METHODS: 50 hypertensive subjects were included in study. Blood pressure was measure by an automatic blood pressure measuring device OMRON after the subjects had rested for at least 10 minutes in a sitting position. Serum uric acid was estimated by Uricase-Peroxidase via ERBA CHEM – 5 PLUS SEMIAUTO ANALYZER. RESULTS: The Serum Uric acid, systolic BP and diastolic BP were increased in hypertensive subjects as compared to normal values. Blood pressure and serum uric acid in male hypertensive subjects were significantly as compared to female hypertensive subjects but diastolic BP was non-significantly increased in male hypertensive subjects as compared to female hypertensive subjects. There was significant positively correlation between serum Uric acid with systolic BP and diastolic BP in hypertensive subjects, male hypertensive subjects and female subjective respectively. CONCLUSION: The serum uric acid was positively correlated with BP in hypertensive patients. So it can be concluded that in clinical practices, measurement of serum uric acid level may help to identify the risk of hypertension. Moreover, further studies can be carried out to lower the serum uric acid level to maintain a low risk of hypertension or to translate high risk of hypertension into a lower risk of hypertension.