Asthma is a chronic respiratory condition characterized by airway inflammation and hyperresponsiveness, leading to breathing difficulties. Conventional treatments primarily focus on symptom control through pharmacological interventions. Random group experimental study was carried out with middle aged asthmatic women. 40 middle aged asthmatic women were selected randomly from Chennai, between the age group of 35 to 45 years and they were divided into two groups I and IT with 20 subjects each. Group I subject were given Yogic practices for 60 minutes, 6 days a week for a total period of twelve weeks. Group II (Control Group) were in active rest. After the experimental period, the two groups were retested again on the same selected dependent variable. Analysis of variance (ANOVA) was used to find out the significant differences between the experimental group and the control group. The test of significance was fixed at 0.05 level of confidence. Yoga have gained attention for their potential to improve respiratory function and overall health in asthmatic patients. This study explores the impact of yoga on asthma, particularly examining the effects on renal function biomarkers: blood urea nitrogen (BUN) and serum creatinine. These markers are not typically associated with respiratory health but can reflect systemic changes due to improved health and reduced oxidative stress from yoga practice. Our findings suggest that yoga may contribute to the management and potential improvement of asthma symptoms, as evidenced by changes in BUN and serum creatinine levels.