ISSN : 2663-2187

Autophagic processes of normal and malignant metabolic pathways

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Aurelian Udristioiu and Manole Cojocaru
» doi: 10.33472/AFJBS.1.3.2019.1-13


Autophagy is a cellular process that maintains the homeostasis of the normal cell, but autophagic dysfunction is associated with human diseases, such as cancer. In normal cells, the initial signal to form auto-phagosomes is by the class III phosphatidyl-inositol (PI) 3 kinase complex consisting of sequence genes, Beclin1/ Atg6 and class III PI3K (Vps34).

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