Postmenopausal women diagnosed with diabetes face specific challenges when it comes to maintaining optimal glycemic control, which significantly affects their overall health and quality of life. The incorporation of physical activity has emerged as a crucial lifestyle approach in the management of glycemic control among persons. The primary objective of this literature review is to conduct an analysis of prior research to enhance our understanding of the effects of exercise on glycemic management, cardiorespiratory fitness, BMI and Quality of life with a specific focus on postmenopausal women diagnosed with diabetes. A systematic exploration of electronic databases, such as PubMed, Scopus, and Web of Science, was undertaken to locate pertinent papers pertaining to exercise therapies in women with postmenopausal diabetes. Exercise is recognized as a crucial strategy that provides benefits that go beyond the initial lowering of glucose levels. Exercise has a crucial role in managing glycemic control by improving insulin sensitivity, facilitating glucose utilization, and impacting body composition. The psychological advantages associated with physical exercise additionally have a role in enhancing adherence to techniques for managing diabetes. Exercise serves as a catalyst for positive transformation across all dimensions of well-being, encompassing physical, emotional, psychological, and social aspects. In our pursuit of strengthening the management of diabetes and improving the well-being of postmenopausal women, it is crucial to acknowledge the significant impact that exercise may have on improving quality of life.