Widespread metabolic syndrome (MBS) is closely linked to poor diet and insufficient exercise, which can lead to more severe disorders like obesity, cardiovascular disease, and type 2 diabetes mellitus. The purpose of this study was to investigate the potential mechanisms underlying the therapeutic effects of Bauhinia variegata extract against a few metabolic and hepatic symptoms seen in MBS rats. Rats were fed a high-fructose diet for 12 weeks in order to induce MBS. For four weeks, BVE (50 mg/kg) was given orally to rats that were MBS-free and normal. The liver index and the hepatic expression of glucose transporter 2 (GLUT2) were measured using liver tissues. Additionally measured were the systolic blood pressure, metabolic parameters, oxidative stress indicators, and the fat/muscle ratio. Our findings shown that giving fructose diet rats BVE dramatically lowered their high systolic blood pressure. Additionally, the alterations in serum insulin, blood glucose, serum lipid profile, and oxidative stress markers were roughly restored to normal levels. Furthermore, BVE therapy reduced blood liver enzyme activity, fat/muscle ratio, and liver index. Here, we demonstrated that, in the experimental model, Bauhinia variegata had a superb effect against metabolic diseases