Global population growth will make it difficult for agricultural output to maintain without depleting vital environmental resources. To address the global food crisis, a proactive and comprehensive strategy will be needed. Modern biotechnology-enhanced crops that have been genetically modified (GM) constitute a significant collection of techniques that may contribute to food security and sustainable agriculture. In a recent symposium organized in conjunction with the 15th IUPAC Global Conference in New Delhi, India, some cutting-edge biotechnology methods were discussed. This presents the latest agricultural biotechnology technologies discussed at the symposium, highlighting unique research and emerging developments in the field. This conversation focuses on how biotechnology for agricultural use fits into the framework of enhanced food security and sustainable agriculture, and how it might be utilized to encourage the ongoing creation and acceptance of advantageous genetically modified crops.