Suicide is a complex public health problem of global importance. Suicidal behavior differs between sexes, age groups, geographic regions, and sociopolitical settings, and variably associates with different risk factors, suggesting etiological heterogeneity. Identifying and preventing suicide attempts and deaths by suicide have represented a considerable challenge for public health authorities. It is believed that the most dramatic increase in suicide mortality increase will be observed in the Third World countries, this is because the socioeconomic and behavioral factors of suicide risk are present in a higher degree than developed countries. Feelings of hopelessness and the intention to kill oneself are not common among Muslims, for whom losing hope in relief by God and self-inflicted death are blasphemous and punishable in the afterlife. However, rates of suicide attempts (parasuicide), which are more likely to be intended to elicit care, have no significant associations with religiousness among Arabs. The crude rate of suicide attempts in Cairo was found to be 38.5 per 100 000. There was a high percentage in the age group 15–44 years, with no major difference between the genders. Single patients represented 53% of the total, with students showing the highest risk (40%).