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Strategies for Teaching Vocabulary Effectively to ESL Students: Identifying and Resolving Challenges : An Emperical Study
Volume 7 | Issue - 1 articles in press
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Perceiving the Self and Others: A Phenomenological Analysis of Character Consciousness in Anita Nair's Fiction
Volume 7 | Issue - 1 articles in press
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Soft Skills: The Catalyst for Critical Thinking in Engineering Education
Volume 7 | Issue - 1 articles in press
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A Comprehensive Framework for Exploring and Evaluating Learning Digital Resources in English Language Classrooms
Volume 7 | Issue - 1 articles in press
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EXPLORATION OF INDIGOFERA PROSTRATE AGAINST OXIDATIVE STRESS AND EVALUATION FOR NEUROPROTECTION IN CHEMICALLY INDUCED NEUROTOXIC RATS
Volume 7 | Issue - 1 articles in press
Characterization and Antileukemic Potential of Annona muricata Leaf Fractions on “MOLT-3” T-Cell Acute Lymphoblastic Leukemia Cells
Main Article Content
Abstract
Results of this research demonstrate that leaf fractions of Annona muricata can cause the T-ALL cell line, molt-3, to undergo apoptosis. To find out what phytochemicals are in the Annona muricata leaf fraction (F4C), we used FTIR and GCMS in this investigation. Different functional groups were detected by FTIR findings, and different phytochemicals were detected by GCMS analysis in the F4C fraction. The cytotoxic efficacy of the F4C fraction against molt-3 cell lines were confirmed byMTT and SRB assays.The F4C treated cells terminated at the G0-G1 phase of the cell cycle, according to cell cycle analysis. It was determined that the substantial drop in MMP staining by JC-1 labelling corresponded to the loss of MMP. Anticancer efficacy against molt-3 cell line is thus demonstrated by Annona muricata leaf fractions.
