Male pattern baldness is a common concern among men, often leading them to seek hair transplant surgery. This study aimed to evaluate the comparative outcomes of hair transplant surgery with and without post-operative minoxidil usage in patients with male pattern baldness. Materials and Methods: A total of 20 male patients, primarily in the age group of 31-40 years, were enrolled in this study. The most common morphological type observed was Grade 2 of Norwood-Hamilton. The patients were divided into two groups: Group 1 included 10 patients who used minoxidil post-operatively, while Group 2 comprised 10 patients who did not use minoxidil. Inclusion criteria encompassed patients suffering from male pattern baldness, while exclusion criteria included patients with autoimmune alopecia, smokers, individuals with underlying systemic diseases, and mentally challenged patients. Results: In the Minoxidil group, the mean pre-operative hair density was 62.05 +/- 4.97, which increased to 76 +/- 4.0 post-operatively. In the group without Minoxidil, the mean pre-operative hair density was 61.8 +/- 3.2, which improved to 67.20 +/- 3.66 post-operatively. After their last visit, patients in the Minoxidil group reported good subjective perception, while those in the group without Minoxidil reported a moderate perception. Conclusion: This study suggests that topical minoxidil may serve as a beneficial adjunct to hair transplant surgery in patients with male pattern baldness. However, larger controlled studies are needed to validate these findings, particularly regarding the potential for minoxidil to reduce post-transplant shedding and expedite regrowth. Additionally, the role of patient age and various graft-related factors in predicting these effects should be further investigated.