In traditional medicine, herbal remedies are often used for treating burns, dermatophytes, and other infectious illnesses. Based on ethno pharmacological and taxonomic data, we tested the antibacterial activities of aqueous and ethanolic extracts of selected medicinal plants in vitro using the agar diffusion-method against selected human pathogenic bacteria. The antimicrobial properties of the leaves of five different plants were tested. Alternative medical practises have long made use of several plant species from all over the globe. There was an extraction process including water and methanol for the powdered leaves of each plant. To dry out the solvent extracts and concentrate them, a rotary flash evaporator was utilised. The dried residue's bactericidal effectiveness was measured by dissolving it in ethanol (1:10 w/v). Various bacteria, including Bacillus cereus, Bacillus megaterium, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus, Streptococcus faecalis, and Yersinia enterocolitica, were employed for in vitro antibacterial screening. Methanol extracts demonstrated more diverse effects on these species than water extracts, indicating that the active components may be present in methanol extracts of all the plants we studied. Many different types of ailments, including as those affecting the immune system, nervous system, digestive tract, respiratory system, skin, and even a high temperature, have been proven to respond well to traditional herbal treatment.